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Masters and Johnson began their secret studies in a small Midwest laboratory working with prostitutes and volunteers who performed more than 10,000 sexual acts in the name of science. They soon became the top experts on sex for more than 40 years, explaining the untold mysteries of orgasm, emotional fulfillment, and sexual dysfunction to millions of Americans. Masters and Johnson were America's ideal couple, but they divorced after 20 years amid a clash of ambitions, betrayal, and jealousies.

Beginning in the 1950s, William Masters and Virginia Johnson convinced hundreds of people to shed their clothes and copulate—in the name of science. For more than 40 years, the pair served as the nation's top experts on love, sex, and intimacy. In this eye-opening work, critically acclaimed biographer Thomas Maier presents an unprecedented look at the research team of Masters and Johnson, their pioneering studies of intimacy, and their lasting impact on the love lives of men and women. Masters of Sex offers a titillating portrait of the team's real-life story.